EGFR mutation testing eLearning modules

• EGFR mode of action

  Binding of EGF to the receptor on the tumour cell surface leads to activation of an intracellular signalling cascade, which is important in the development and survival of solid tumours.
  The EGFR gene can have mutations that cause the EGFR to be permanently activated.
  Patients who have tumours that contain activating EGFR mutations are likely to respond well to EGFR tyrosine kinase inhibitors.

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• Importance of EGFR mutation testing

  Why is EGFR mutation testing important for patients?
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  EGFR mutations, their role in lung cancer and treatment
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• A guide to EGFR mutation testing

  Information on reviewing tumour samples
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  DNA extraction methods
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  Testing technologies, and mutation detection techniques
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  Locate a testing lab
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